The Green Bay Packers traveled on the road to face the Buffalo Bills. The Bills were able to lead the Packers at half time with a 10-0 lead, capitalizing on an interception return for a touchdown by London Fletcher. In the second half, the Packers tied the score with a touchdown pass to Donald Driver. The Bills were able to score in the fourth quarter with 43&#160;yard touchdown pass to receiver Lee Evans. The Packers drove the ball deep to the one-yard line, but on first down the ball is intercepted and returned deep in Packer territory. The Bills were able to score three plays later to increase the lead by 14 and earn a victory.

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