Coming off their win over the Bengals on Thanksgiving, the Jets traveled to Foxborough in Monday Night Football game with the New England Patriots. In the first quarter, the Patriots took the early lead, with a 41-yard field goal from kicker Shayne Graham, followed by a 1-yard touchdown run from running back BenJarvus Green-Ellis and a 25-yard touchdown pass from quarterback Tom Brady to wide receiver Deion Branch. In the second quarter, the Jets got on the board, with a 39-yard field goal from kicker Nick Folk, in what would be the Jets' only score of the game. Later in the second quarter, the Patriots replied, with Brady throwing a 4-yard touchdown pass to wide receiver Brandon Tate. The Patriots continued their offensive onslaught in the third quarter, with Brady throwing an 18-yard touchdown pass to wide receiver Wes Welker. In the fourth quarter, Brady threw a 1-yard touchdown pass to tight end Aaron Hernandez, followed by a 5-yard touchdown run from Green-Ellis. With the loss the Jets dropped to 9-3 and second place in the AFC East.

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