The Rams began their 2007 campaign at home against the Carolina Panthers.  In the first quarter, St. Louis trailed early as Panthers QB Jake Delhomme completed a 10-yard TD pass to WR Drew Carter.  The Rams would tie the game with QB Marc Bulger completing a 3-yard TD pass to WR Torry Holt.  In the second quarter, St. Louis would take the lead with kicker Jeff Wilkins getting a 42-yard field goal for the only score of the period.  In the third quarter, Wiklins helped the Rams' lead with a 28-yard field goal.  However, this was all wiped out as Delhomme completed a 68-yard TD pass to WR Steve Smith.  In the fourth quarter, Carolina took over for the remainder of the game as kicker John Kasay nailed a 34-yard field goal, Delhomme and Carter hooked up with each other again on a 9-yard TD pass, and Kasay finished the game with 32-yard field goal. The game was notable when offensive tackle Orlando Pace suffered a season-ending injury. This severely hurt the Rams' offense.

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