Q: After back-to-back sub-par performances by the Patriots offense, they faced Derek Carr and the lowly Raiders in their 2014 home opener looking to have their first breakout performance of the season. After both teams punted on their opening drive, the Raiders reached the Patriots 31 and struck first blood on a 49-yard field goal by Sebastian Janikowski. After both teams punted again, the Patriots embarked on a 15 play, 84-yard drive, converting four third-downs,  and scoring on Brady's 6-yard touchdown pass to Gronkowski midway through the second quarter to take a 7-3 lead. The Raiders punted on their next drive, and Marquette King punted only 22 yards to midfield. With the great field position, the Patriots drove all the way to the Raiders 2, but their red zone struggles continued, and they settled for a 20-yard field goal by Gostkowski, giving them a 10-3 lead at halftime. Strong defense continued in the second half. The Raiders drove deep into Patriots territory early in the second quarter, but could only score on a 37-yard field goal by Janikowski. Following a Patriots punt, the Raiders drove from their own 14, to the Patriots 37, but a false start penalty on guard Donald Penn made it 3rd-and-15, and then Carr completed a 13-yard pass to James Jones to the Patriots 29, bringing up a 4th-and-2. The Raiders decided to settle with Janikowski's 47 yard field goal, making the score 10-9. Matthew Slater returned the ensuing kickoff 26 yards to the Patriots 41. With the good field position, the Patriots drove to the Raiders 2 again, but were once again held out of the end zone, and increased their lead to 13-9 on another 20-yard field goal by Gostkowski. After the Raiders went three-and-out, the Patriots marched 63 yards culminating with Gostkowski's 36-yard field goal, increasing the lead to 16-9 midway through the fourth quarter. The Raiders, though, couldn't muster up any offense against the Patriots and they went three-and-out again, but the Patriots failed to put the game away and punted. In just three plays the Raiders reached Patriots territory, but two plays later, on 3rd-and-7 at the Patriots 30-yard line, Carr threw an incomplete pass seemingly bringing up a do-or-die 4th down, but Ryan was called for pass interference moving the ball to the Patriots 6-yard line. On the very next play, Darren McFadden scored on a 6-yard touchdown run, but the score was nullified by a holding penalty on Raiders left guard Gabe Jackson. On the next play, Carr's pass attempt was tipped and intercepted by Vince Wilfork with 0:51 seconds left, which sealed the win for the Patriots. Tom Brady had his best game to date, despite being pressured relentlessly by the Oakland defensive line, including being sacked twice, completing 24 of 37 passes for 234 yards, with 1 touchdown and no interceptions. The running game struggled, with Ridley leading the team with only 54 yards on 19 carries. Julian Edelman was the leading receiver for either team, with 10 catches for 84 yards. Rob Gronkowski continued to slowly work himself into the offense catching only 3 passes for 44 yards, but also caught the only touchdown. Derek Carr had a sub-par day, going 21 of 34 for only 174 yards, with no touchdowns and an interception. Both defenses were spectacular holding the opposing offense to under 300 yards of offense (241 for the Raiders, 297 for the Patriots). With the win the Patriots advanced to 2-1 and Brady won his 150th career game, 3rd most by a starting quarterback in NFL history.
How many points were the Patriots ahead by at halftime?

A: 7
P: Kuroda Nagamasa  was a daimyō during the late Azuchi-Momoyama and early Edo periods. He was the son of Kuroda Kanbei, Toyotomi Hideyoshi's chief strategist and adviser. His child-hood name was Shojumaru . In 1577, when Nagamasa was a small child, his father was tried and sentenced as a spy by Oda Nobunaga. Nagamasa was kidnapped and nearly killed as a hostage. With the help of Yamauchi Kazutoyo and his wife, Takenaka Hanbei ended up rescuing him. After Oda Nobunaga was killed in Honnō-ji incident of 1582, Nagamasa served Toyotomi Hideyoshi with his father and participated in the invasion of the Chūgoku region. Nagamasa also participated in the first Korean campaign , commanding the Third Division of 5000 men during the first invasion 1592-1593. In the second part of the campaign  he held command in The Army of the Right. He took part in the Battle of Sekigahara in the year 1600 serving under Tokugawa Ieyasu. His men killed Shima Sakon, securing victory for the Eastern army. As a reward for his service at Sekigahara, Tokugawa granted Nagamasa Chikuzen  - 520.000 koku - in exchange for his previous fief Nakatsu, Buzen.Later he participated in the Osaka Castle campaigns.
Answer this: How many years after Nagamasa took part in the first invasion did he take part in the Battle of Sekigahara?

A: 7
Problem: Relationship between concentrations and effects  Drowsiness, dissociative, and psychosis-like effects (e.g., hallucinations, delirium) are reported in patients treated with ketamine starting at circulating concentrations of around 50 to 200 ng/mL (210-841 nM), while analgesia begins at levels of approximately 100 to 200 ng/mL (421-841 nM). The typical intravenous antidepressant dosage of ketamine used to treat depression is low and results in maximal plasma concentrations of 70 to 200 ng/mL (294-841 nM). Circulating concentrations of around 2,000 to 3,000 ng/mL (8,413-12,620 nM) are employed during anesthesia, and patients may start to awaken once levels of ketamine have decreased to about 500 to 1,000 ng/mL (2,103-4,207 nM). There is wide variation in the peak concentrations of ketamine that have been reported in association with anesthesia in the literature, with values ranging from 2,211-3,447 ng/mL (9,300-14,500 nM) to as high as 22,370 ng/mL (94,100 nM). Biological activity concentrations of ketamine are lower than total plasma levels due to plasma protein binding, although plasma protein binding is relatively low with ketamine (approximately 12 to 47% protein-bound). Concentrations of ketamine in the brain have been reported to be several-fold higher than in plasma.
Answer this question based on the article: Which medication reports effects like drowsiness, dissociative and psychosis starting at a higher concentration, ketamine or analgesia?
A:
analgesia