Answer based on context:

The Redskins entered this Week 1 matchup against the Steelers having lost five consecutive games against Pittsburgh dating back to 1991. They scored an average of 8.2 points per game in those five losses. The Redskins' 22-point defeat was their worst in a Week 1 game in 15 years. It was also their worst opening day home loss since 1966. The Redskins defense had a very hard time containing DeAngelo Williams as he exploded for 143 rushing yards and the Steelers explosive receiving corps of Antonio Brown and Eli Rogers who would go on to have strong performances.

How many points did the Redskins lose by?
22