Hoping to rebound from their road loss to the Steelers, the Chargers went home for a Week 12 Sunday Night game with the Indianapolis Colts.  In the first quarter, San Diego trailed early as Colts kicker Adam Vinatieri made a 23-yard field goal.  In the second quarter, the 'Bolts took the lead as kicker Nate Kaeding got a 35-yard field goal, while QB Philip Rivers completed a 39-yard TD pass to WR Vincent Jackson.  Indianapolis would tie the game with QB Peyton Manning completing a 13-yard TD pass to WR Anthony Gonzalez. In the third quarter, the Colts took the lead with Manning's 1-yard TD pass to RB Dominic Rhodes.  In the fourth quarter, Indianapolis increased their lead as Vinatieri got a 38-yard field goal.  San Diego would rally to tie the game as Rivers completed a 1-yard TD pass to rookie FB Jacob Hester, while Kaeding made a 47-yard field goal.  However, the Colts came out on top as Vinatieri nailed the game-winning 51-yard field goal. With the loss, the Chargers fell to 4-7. This marked the 5th game the Chargers lost in the last 24 seconds.

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